| Sertraline | |
| Indication | • Depression
• Obsessive-Compulsive Disorder • Panic Disorder • Posttraumatic Stress Disorder • Social Anxiety Disorder • Premenstrual Dysphoric Disorder • Off-label: • Pruritus |
| Contraindication | • To be used with caution in Children and adolescent
• Hypersensitivity • Risk of switch to Mania • Gastrointestinal bleeding • Abnormal Electrocardiogram changes • History of seizure disorder • Risk of Hyponatremia • Angle closure glaucoma • Sexual dysfunction • Concomitant use with few other drugs like pimozide or thioridazine or Monoamine Oxidase Inhibitors, other |
| Benefit | • Improvement in depressive symptoms
• Safer than other antidepressants in pregnancy and breastfeeding • Improves ejaculation time in patients with premature ejaculation • Safe in patients with cardiac problems • Safe in patients taking multiple medications for other medical problems |
|
Adverse effects (usually decreases in 3-4 weeks of therapy, usually reversible) |
• Diarrhoea
• Nausea • Headache • Insomnia • Ejaculation disorder • Dizziness • Dry mouth • Fatigue • Drowsiness • Avoid abrupt withdrawal |
