| Fluoxetine | |
| Indication | • Depression
• Obsessive-Compulsive Disorder • Panic Disorder • Bulimia Nervosa • Premenstrual Dysphoric Disorder • Off-label: • Fibromyalgia • Migraine • Hot Flashes Caused by Hormonal Chemotherapy • Raynaud Phenomenon |
| Contraindication | • To be used with caution in Children and adolescent
• Hypersensitivity • Breastfeeding • Risk of switch to Mania • Gastrointestinal bleeding • Abnormal Electrocardiogram changes • History of seizure disorder • Risk of Hyponatremia • Angle closure glaucoma • Sexual dysfunction • Concomitant use with few other drugs like pimozide or thioridazine or Monoamine Oxidase Inhibitors, other |
| Benefit | • Improvement in depressive symptoms
• May cause weight reduction • Long acting thus require frequent dosing • Improves ejaculation time in patients with premature ejaculation |
|
Adverse effects (usually decreases in 3-4 weeks of therapy, usually reversible) |
• Insomnia
• Nausea • Headache • Weakness • Diarrhoea • Somnolence • Asthenia • Anxiety • Nervousness • Tremor • Anorexia |
